Wednesday, July 14, 2021

Which Vaccine is Better For Covid19?

STILL CONFUSED WHICH VACCINE TO TAKE?

CURRENTLY, All the vaccine that are available in market are safe. They are made with precautions and experts have taken all safety measures to make them

Which Vaccine is Better For Covid19?
Which Vaccine is Better For Covid19?


Though, all vaccine provide immunity but each one is unique in itself. BUT as the expert suggest that the 3rd wave is on its way. The only way to stop this pandemic is Vaccination. Ever since the vaccination has been started in India . Question like Which vaccine is better? are flooded on internet.

But why to get vaccinated?

Vaccine reduces the risk of infection in your body. And, once more of the population is vaccinated, those further chances of spreading virus is reduced thanks to something called herd immunity. So, getting vaccinated not only reduces your chance of being infected, it also contributes to community protection, reducing the likelihood of virus transmission..

What are the benefits of getting a COVID-19 vaccine?

Vaccine might:
  •  Prevent you from getting COVID-19 or from becoming seriously ill or dying due to COVID-19
  • Prevent you from spreading the COVID-19 virus to others
  •  Add to the number of people in the community who are protected from getting COVID-19 — making it harder for the disease to spread and contributing to herd immunity
  • Prevent the COVID-19 virus from spreading and replicating, which allows it to mutate and possibly become more resistant to vaccines.

CURRENTLY, In INDIA vaccine provided by Government in govt Hospital are majorly COVISHIELD AND COVAXIN

Vaccine available in INDIAN Markets-

  1. Covisheild
  2. Covaxin
  3. Moderna
  4. Sputnik V
  5. Pfizer

UPCOMING Vaccine In INDIA?

Vaccine are at different stages of trials in India to test safety and efficacy include:
  • ZyCov-Di, being developed by Ahmedabad-based Zydus-Cadila
  • Hyderabad-based Biological E to produce the vaccine developed by US firm Johnson & Johnson
  • HGCO19, India's first mRNA vaccine made by Pune-based Genova in collaboration with Seattle-based HDT Biotech Corporation, using bits of genetic code to cause an immune response
  • A nasal vaccine by Bharat BioTech

COVISHIELD

The Oxford-AstraZeneca vaccine is being manufactured locally by SII.

The vaccine is made from a weakened version of a common cold virus (known as an adenovirus) from chimpanzees. It has been modified to look more like coronavirus - although it can't cause illness.

When the vaccine is injected into a patient, it prompts the immune system to start making antibodies and primes it to attack any coronavirus infection.

The jab is administered in two doses given between four and 12 weeks apart. It can be safely stored at temperatures of 2C to 8C

Dosage: Two doses, four to 12 weeks apart

How effective is Covishield?

International clinical trials of the vaccine showed that when people were given a half dose and then a full dose, effectiveness hit 90%.

However, unpublished data suggests that leaving a longer gap between the first and second doses increases the overall effectiveness of the jab - in a sub-group given the vaccine this way it was found to be 70% effective after the first dose

COVAXIN

Covaxin is an inactivated vaccine which means that it is made up of killed coronaviruses, making it safe to be injected into the body.

Bharat Biotech, a 24-year-old vaccine maker, used a sample of the coronavirus, isolated by India's National Institute of Virology.

When administered, immune cells can still recognise the dead virus, prompting the immune system to make antibodies against the pandemic virus.

Dosage: 2 doses, three weeks apart

How effective is Covaxin?

The study found that Covaxin had an efficacy of 93.4% against severe COVID-19 disease, and an overall vaccine efficacy of 77.8% against symptomatic infections confirmed by PCR tests. Against asymptomatic COVID-19, the efficacy was 63.6%. . The vaccine also conferred 65.2% protection against symptomatic infection with the Delta variant, at least two weeks after the second dose.

Pfizer-BioNTech

On December 11, 2020, this became the first COVID-19 vaccine to receive an Food and Drug Administration (FDA)

Dosage: Two shots, 21 days apart

How effective is PFIZER?

This is a messenger RNA (mRNA) vaccine, Unlike vaccines that put a weakened or inactivated disease germ into the body, the vaccine delivers a tiny piece of genetic code from the SARS CoV-2 virus to host cells in the body, essentially giving those cells instructions, or blueprints, for making copies of spike proteins The spikes do the work of penetrating and infecting host cells. These proteins stimulate an immune response, producing antibodies and developing memory cells that will recognize and respond if the body is infected with the actual virus. 95% efficacy in preventing COVID-19 in those without prior infection. In clinical trials, the vaccine was 100% effective at preventing severe disease.

Moderna’s vaccine was the second one authorized for emergency use in the U.S.—This vaccine, using the same technology as the Pfizer-BioNTech one and with a similarly high efficacy at preventing symptomatic disease. There are two key differences: The Moderna vaccine can be shipped and kept in long-term storage in standard freezer temperatures, and stored for up to 30 days using normal refrigeration.

Dosage: Two shots, 28 days apart

How effective is Moderna?

Similar to the Pfizer vaccine, this vaccine sends the body’s cells instructions for making a spike protein that will train the immune system to recognize it. The immune system will then attack the spike protein the next time it sees one (attached to a real SARS CoV-2 virus). It is 94.1% effective at preventing symptomatic infection in people. The efficacy rate drops to 86.4% for people ages 65 and older

Sputnik V

The Russian COVID-19 vaccine Sputnik V is an adenoviral-based, two-part vaccine against the coronavirus. Initially produced in Russia, Sputnik V uses a weakened virus to deliver small parts of a pathogen and stimulate an immune response. The vaccine reduces the time taken for the actual development of immunity

Dosage: One shots

How effective is Sputnik V ?

Efficacy of Sputnik V against COVID-19 was reported at 91.6%. The figure is based on the analysis of data on 19,866 volunteers, who received both the first and second doses of the Sputnik V vaccine or placebo at the final control point of 78 confirmed COVID-19 cases. It is a vector vaccine based on adenovirus DNA, in which the SARS-CoV-2 coronavirus gene is integrated. Adenovirus is used as a “container” to deliver the coronavirus gene to cells and start synthesizing the new coronavirus's envelope proteins, “introducing” the immune system to a potential enemy.

What are the possible side effects of a COVID-19 vaccine?

A COVID-19 vaccine can cause mild side effects after the first or second dose, including:
  • Pain, redness or swelling where the shot was given
  • Fever
  • Fatigue
  • Headache
  • Muscle pain
  • Chills
  • Joint pain
  • Nausea and vomiting
  • Feeling unwell
  • Swollen lymph nodes
“As a rough comparison, recent figures from Public Health Scotland suggested that at least two weeks after the second dose, the Pfizer-BioNTech vaccine was 79% effective against the Delta variant, while the Oxford-AstraZeneca was 60% effective. However, different trial methodologies make it impossible to directly compare the relative efficacies of the various vaccines.”

 

CONCLUSION

THOUGH Vaccination in india is going fast still, only 10% of the population is vaccinated. Vaccination is only the way to defeat covid.

Hope you have got all the information regarding the vaccine. If you have any query regarding any topic contact us at healthifytalk@gmail.com

Some QNA regarding vaccines-

Q1-Can a COVID-19 vaccine give you COVID-19?

No. The vaccines don't use the live virus that causes COVID-19.


Q2-Are their any allergic reaction to a COVID-19 vaccine?

You might have an allergic reaction if you experience these signs within four hours.

· Continuous shortness of breath or wheezing

· Swelling of the lips, eyes or tongue

· Redness, swelling or itchiness in areas of the body


Q3-What are the long-term side effects of the COVID-19 vaccines?

COVID-19 vaccines clinical trials only started in the summer of 2020, it is not clear if these vaccines will have long-term side effects. However, it rarely cause long-term side effects.

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